Melanoma Vaccines
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چکیده
منابع مشابه
Melanoma Vaccines
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متن کاملMelanoma vaccines.
The distribution of iron and iron binding proteins (IBP) have been compared with control spleen tissue in an attempt to establish a pattern of staining restricted to Hodgkin's disease (HD). All but one of the HD spleens examined stained for ferritin, which was largely present in red pulp dendritic macrophages (DM). In spleens histologically involved with HD heavy deposits of ferritin were seen ...
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Vaccines are a promising but still experimental treatment for melanoma. They are intended to stimulate immune responses against melanoma and by so doing, increase resistance against and slow the progression of this cancer. Key requirements for vaccines to be effective are that they contain antigens that can stimulate tumor-protective immune responses and that some of these antigens are present ...
متن کاملThe unfulfilled promise of melanoma vaccines.
INTRODUCTION There is a sense of impatience with the unfulfilled, decades-long promise of melanoma vaccines. The promise is kept alive by a series of encouraging small trials such as the randomized trial reported by Bystryn et al. (1) in this issue, by remarkable progress in the molecular definition of human melanoma antigens recognized by the immune system, and by opportunities for vaccine con...
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Cell surface gangliosides show altered patterns of expression as a consequence of malignant transformation and have therefore been of interest as potential targets for immunotherapy, including vaccine construction. One obstacle has been that some of the gangliosides that are overexpressed in human cancers are poorly immunogenic in humans. A case in point is GD3, a prominent ganglioside of human...
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ژورنال
عنوان ژورنال: Surgical Clinics of North America
سال: 2014
ISSN: 0039-6109
DOI: 10.1016/j.suc.2014.07.005